Question

. How many pore-forming \(\mathbf{K}^{+}\)channel subunits assemble to form a functional channel? a. One b. Two c. Four d. None of the above

Short answer

Answer: Four

Step-by-step solution

Understand the structure of potassium channels

Potassium channels are transmembrane proteins that facilitate the selective transport of potassium ions across cell membranes. They play a crucial role in many physiological processes such as nerve signal transmission, muscle contraction, and maintaining the resting membrane potential. The subunits that form potassium channels can assemble to create a central pore through which potassium ions can pass.

Identify the correct number of subunits

It is well-established in the literature that a functional potassium channel is typically formed by the assembly of four pore-forming subunits. This creates the complete channel structure that allows for proper ion selectivity and gating.

Choose the correct option

Based on the information above, we can see that the correct answer is: c. Four A functional potassium channel is formed by the assembly of four pore-forming K+ channel subunits.