When eye drops like timolol are instilled, a portion may be absorbed into the bloodstream, potentially leading to systemic effects — meaning that parts of the body other than the eyes may be affected. For medications like timolol, when used for treating POAG, systemic effects can include changes in heart rate, blood pressure, and respiratory function due to its beta-blocking properties.
Minimizing these systemic effects is a crucial aspect of treatment, especially in patients who may have comorbid conditions that could be exacerbated by these side effects. Techniques such as punctal occlusion, where pressure is applied to the inner canthus after instillation, can be used to reduce systemic absorption. This method blocks the tear duct, which connects to the nasal cavity and can transport the medication into the systemic circulation more quickly. Educating patients on the importance of these techniques during administration can significantly enhance the safety and efficacy of their treatment.
- Consideration: For individuals on beta-blockers or with pre-existing respiratory conditions, it's vital to monitor for systemic side effects and consult healthcare providers regularly.
- Recommendation: Always report any unusual symptoms to a healthcare professional promptly after starting a new ocular medication.