Problem 1
The typical clinical syndrome associated with rotavirus infection is: A. acute gastroenteritis of young adults. B. acute bronchiolitis of infants. C. acute hepatitis. D. nausea, vomiting, and diarrhea in infants and young children. E. acute paralytic syndrome.
Problem 2
Rotaviruses differ from polioviruses in that rotaviruses: A. infect via the fecal-oral route. B. lack an envelope. C. can undergo genetic reassortment. D. do not contain any enzymes. E. have an icosahedral structure.
Problem 3
The diagnosis of a rotavirus infection: A. can be made, in most cases, on the basis of the clinical presentation. B. can be made based upon the detection of viral capsid antigens in stool samples. C. is routinely made by electron microscopy of suitably treated stool samples. D. can only be made on epidemiologic grounds (for example, if there is an epidemic). E. must be made rapidly so that specific antiviral therapy is initiated as soon as possible.
Problem 4
Appropriate treatment of rotavirus infection includes which of the following? A. Fluid and electrolyte replacement B. Antiviral drugs targeting membrane fusion C. Metronidazole D. Antiviral drugs targeting reverse transcriptase E. Antiviral drugs targeting proteolytic processing
