Which of these statements about enzyme-catalyzed reactions is true?
a. The rate of reaction is independent of temperature.
b. The rate of all enzyme-catalyzed reactions is decreased when the
\(\mathrm{pH}\) is lowered from 7 to 2 .
c. The rate of reaction is independent of substrate concentration.
d. Under given conditions of substrate concentration, pH, and temperature, the
rate of product formation varies directly with enzyme concentration up to a
maximum, at which point the rate cannot be increased further.