Question

Regarding connective tissue, which of the following statements is false? a. It is mostly formed by tightly connected fibroblasts. b. Its strength is determined by the matrix. c. Some specialized cells produce histamine. d. It offers support to the softer organs of the body. e. Cartilage is rich in collagen fibers and water.

Short answer

Statement (a) is false.

Step-by-step solution

- Understand Connective Tissue

Connective tissue is a type of tissue in the body that provides structural support and fills spaces between organs. It includes various types such as bone, cartilage, adipose (fat) tissue, and blood.

- Analyze Statement (a)

Statement (a) suggests that connective tissue is mostly formed by tightly connected fibroblasts. Fibroblasts are indeed a key component but connective tissue is characterized by a sparse distribution of cells embedded in an extracellular matrix, not tightly connected.

- Review Other Statements for Accuracy

Statement (b) correctly states that the strength of connective tissue is determined by the matrix, which can be composed of collagen, elastin, and other fibers. Statement (c) is accurate as some specialized cells in connective tissue, such as mast cells, produce histamine. Statement (d) is also true because connective tissue indeed offers support to softer organs. Finally, statement (e) is correct because cartilage is rich in collagen fibers and water.

- Identify the False Statement

Comparing all the statements, it becomes clear that statement (a) is the one that is false. Connective tissue is not mostly formed by tightly connected fibroblasts; it is composed of cells dispersed in an extracellular matrix.

Key concepts

fibroblasts

Fibroblasts are a type of cell found in connective tissue. They play a crucial role in maintaining the structural integrity of this tissue by secreting the extracellular matrix and collagen fibers.

Despite being vital, they are not densely packed. Instead, they are scattered throughout the extracellular matrix. This distribution allows the fibroblasts to provide structural support while also permitting flexibility.

Fibroblasts are active in wound healing and tissue repair. They can differentiate into different cell types needed for tissue repair.
Both their presence and activity ensure that connective tissue remains resilient and can adapt to various physiological needs.

extracellular matrix

The extracellular matrix (ECM) forms the bulk of connective tissue. It consists of a network of proteins and other molecules that provide structural and biochemical support to surrounding cells.

Key components of the ECM include collagen, elastin, and proteoglycans. Collagen provides tensile strength, elastin allows tissues to return to their original shape after stretching, and proteoglycans add compressive strength and hydration.

Apart from giving strength, the ECM also plays a role in cell communication. It offers a scaffold that helps cells attach and interact, influencing cell behavior and tissue function.

supportive tissue

Supportive tissue in the body includes all types of connective tissues that provide structural and functional support. Examples are bone, cartilage, adipose tissue, and blood.

These tissues help protect softer organs and maintain the body's structural integrity.

• Bone: Provides rigid support and protection for organs. It also facilitates movement by serving as points of attachment for muscles.


• Cartilage: Offers flexible yet strong support, especially in joints where it cushions and reduces friction.


• Adipose tissue: Stores energy and insulates the body.


• Blood: Transports nutrients, gases, and waste products throughout the body.

Each type of supportive tissue, with its unique properties, works together to uphold the body's architecture and functionality.