Total parenteral nutrition (TPN) is a life-sustaining therapy for patients who cannot receive nutrition through regular food intake or enteral feeding. It involves the administration of nutrients directly into the bloodstream through a central venous catheter. While TPN can be a critical intervention, it poses a risk for central line-associated bloodstream infections (CLABSIs), which can be life-threatening.
Preventing infections in TPN is multifaceted. Nurses must ensure that TPN containers are changed at least every 24 hours—not 48 hours as previously thought—to reduce microbial growth. Similarly, the tubing used for TPN should be replaced daily, as per evidence-based guidelines. Monitoring glucose levels is also pivotal, as hyperglycemia can increase the risk of infection. Furthermore, elevating the head of the bed can help prevent aspiration but is not directly related to central line infection prevention. These steps, along with rigorous infection control practices, are key to safeguarding patients from infection risks associated with TPN.
- Change TPN containers at least every 24 hours to minimize infection risk.
- Replace TPN tubing daily in accordance with evidence-based practices.
- Regular glucose monitoring is critical for detecting and managing hyperglycemia.