Chapter 28: Q13P (page 1080)
Question: Draw the molecular formula of the covalently modified histone side chain of acetyllysine. How does this modification alter the chemical properties of the side chain?
The molecular formula of the covalently modified histone side chain of acetyllysine is:
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Compare regulation by the lack repressor the trip repressor.
Question: Monomethylation of histone Arg residues can be reversed by the action of a peptidyl arginine deiminase, which requires water to remove the methyl group along with the amino group of Arg. Draw the structure of the resulting amino acid side chain and identify this nonstandard amino acid.
Question: Explain why a deficiency of the vitamin folic acid could lead to the undermethylation of histones and DNA.
Question: Why is it disadvantageous for single-celled eukaryotes such as yeast to undergo apoptosis?
Explain why inactivation of the sequence of the lac operator almost completely abolishes repression of the lac operon
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