Question

Why is chromatin remodeling necessary for efficient gene expression?

Short answer

DNA itself can be methylation and that also regulates gene expression, generally to turn off the gene.

Step-by-step solution

Functional RNA.

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein-coding genes such as transfer RNA or small nuclear RNA genes, the product is a functional RNA.

Histones.

Chromatin is the material that makes up a chromosome that consists of DNA and protein. The major proteins in chromatin are called histones. They act as packaging elements for DNA.

Chromatin remodeling plays a central role in the regulation of gene expression by providing the transcription machinery with dynamic access to an otherwise tightly packaged genome.