Question

Question: Kinases are enzymes that transfer a phosphoryl group from a nucleoside triphosphate. Which of the following are valid kinase-catalyzedreactions?
(a)
(b)

Short answer

The correct answer is .

Step-by-step solution

Introduction

Kinase-catalyzed reactions are chemical processes that are catalyzed by kinases. This process involves these enzymes transferring one phosphoryl group from a nucleoside triphosphate to organic molecules. By phosphorylating other proteins, the kinase enzymes change their structure. Adenosine triphosphate (ATP) is the main source of phosphoryl groups (ATP).

In the solution (a), ADP + CMP →AMP + CDP

"$ADP+CMP\to AMP+CDP$" is a kinase-catalyzed reaction that isn't genuine. The phosphoryl group is transferred from ADP rather than ATP in this process.

Thus, Option (a) is incorrect.

In the solution (b), AMP + ATP →2ADP

The enzyme adenylate kinase catalyzes the production of ADP from ATP. In this reaction, one phosphate group from ATP is transferred to AMP to generate two molecules of adenosine diphosphate (ADP).

$AMP+ATP\to 2ADP$

Thus, Option (b) is correct.

Interpretation

Thus, in the second reaction, the phosphorylation of ATP to ADP occurs. $AMP+ATP\to 2ADP$ is a valid kinase-catalyzed reaction.