Chapter 23: Q3P (page 828)
How does 2-azahypoxanthine, a fungal product that stimulates plant growth, differ from guanine?
Short Answer
Nitrogen is a part of the ring structure of 2-azahypoxanthine in the place of a second carbon of the guanine.
Chapter 23: Q3P (page 828)
How does 2-azahypoxanthine, a fungal product that stimulates plant growth, differ from guanine?
Nitrogen is a part of the ring structure of 2-azahypoxanthine in the place of a second carbon of the guanine.
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Get started for freeList all the enzymes of nucleotide biosynthesis that use glutamine as an amino group donor.
The compound shown here is being tested as an anticancer agent.
(a) Explain why it inhibits CTP production.
(b) Explain why it also inhibits phospholipid synthesis.
Rats are given cytidine that is14C-labeled at both its base and ribose components. Their DNA is then extracted and degraded with nucleases. Describe the labeling pattern of the recovered deoxycytidylate residues if deoxycytidylate production in the cell followed a pathway in which (a) intact CDP is reduced to dCDP, and (b) CDP is broken down to cytosine and ribose before reduction.
Which reaction of the IMP AMP pathway resembles a reaction of the urea cycle?
Certain glutamine analogs irreversibly inactivate enzymes that bind glutamine. Identify the nucleotide biosynthetic intermediates that accumulate in the presence of those compounds.
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