Chapter 23: Q18P (page 829)
Describe how the fumarate produced by the purine nucleotide cycle could be catabolized to CO2.
Short Answer
The citric acid cycle can catabolize the fumarate generated by the purine nucleotide cycle to CO2.
Chapter 23: Q18P (page 829)
Describe how the fumarate produced by the purine nucleotide cycle could be catabolized to CO2.
The citric acid cycle can catabolize the fumarate generated by the purine nucleotide cycle to CO2.
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Describe how purine catabolism is related to SCID, muscle function, and gout.
Normal cells die in a nutrient medium containing thymidine and methotrexate, whereas mutant cells defective in thymidylate synthase survive and grow. Explain.
Describe the reactions that convert IMP to ATP and GTP.
Describe the importance of multifunctional enzymes in nucleotide biosynthesis.
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