Question

Why might transcriptomic and proteomic analyses reveal different information about the metabolic activity of a particular tissue?

Short answer

Transcriptomic gives information about the metabolic activity of RNA molecules in a cell, and proteomic explains protein's metabolic activity because of the functional difference between RNA and proteins.

Step-by-step solution

The concept of transcriptomics and proteomics

Transcriptomics is a study that interprets the RNA molecules in a cell, including non-coding RNAs and small RNAs.

Proteomics studies proteins, including their function, structure, composition, and activities that take place in cells.

Transcriptomic and proteomic studies give different information

Transcriptomics and proteomics give different information about a cell or tissue.The former interprets the data of RNA molecules in a cell, whereas the latter gives complete information about proteins in a cell.

A cell's protein amount is greater than the amount of mRNA. Hence, both analyses show different metabolic activity in a tissue due to their functional difference.