Question

What is the function of the pre-replication complex?

Short answer

The pre-replication complex is a protein complex that forms all the sites of the origin of replication (Ori) during the initiation step of DNA replication.

Step-by-step solution

Pre-replication complex assembling

The pre-replication complex is assembled by continuous and sequential binding of conserved proteins.

This process of assembling occurs at the end of the M phase.

Function of Pre-replication complex

Prior to the initiation of DNA replication, a multi protein assembly called pre-replication complex assembling occurs.

The pre-replication complex is formed at all origins of replication.

The end result of the pre-replication complex is the loading of MCM2-7 replicative helicase onto the origin DNA.

Thus, a pre-replication complex is required for DNA replication.