Question

What is the significance of different DNA binding properties of prokaryotic RNA polymerase core enzyme and haloenzyme?

Short answer

RNA polymerase is an enzyme that uses in RNA transcription

Step-by-step solution

Step 1: Core Enzymes

It consists of the subunit that has catalytic activity.

For example - the RNA polymerase enzyme doesn't have the sigma factor.

Haloenzyme

A biochemical compound that is formed by the combination of enzyme and coenzyme is called haloenzyme.

DNA binding properties of RNA polymerase

Once the open complex has been formed, transcription proceeds without dissociating the enzyme from the template, Processively is accomplished without a prominent clamp-like structure. However, the RNAP itself functions as a sliding clamp by binding tightly but flexibly to the DNA RNA complex.

Significance of different DNA binding properties of prokaryotic RNA polymerase

The tight association between RNAP and DNA and their multiple attachment sites explain why a transcription complex does not entirely dissociate from a DNA temple. Hence, this is the significance of different DNA binding properties of prokaryotic RNA polymerase core enzyme and haloenzyme