Chapter 8: Q20P. (page 243)
A protein that fails to fold properly in the endoplasmic reticulum may undergo O-mannosylation. Draw the structure of the resulting modified amino acid residue.
A protein linked with sugar moiety by the amino acid serine or threonine. O-linked oligosaccharides are linked to serine or threonine.
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Retroviruses bearing oncogenes will infect cells from their corresponding host animal but will usually not transform them to cancer cells.
Yet these retroviruses will readily transform immortalized cells derived from the same organism. Explain.
Draw a Haworth projection of D-glucose and identify it as an α or β anomer.
Are (a) D-glucitol, (b) D-galactitol, and (c) D-glycerol optically active?
A growth factor that acts through a receptor tyrosine kinase stimulates cell division. Predict the effect of a viral protein that inhibits the corresponding protein tyrosine phosphatase.
Hydroxylamine converts cytosine to the compound
shown below.
With which base does this modified cytosine pair? Does this generate a
transition or a transversion mutation?
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