Question

In certain situations, a glycosyltransferase catalyzes the addition of a GlcNAc group to an arginine residue in a protein. Draw the structure of the modified arginine side chain.

Short answer

Arginine has nucleophiles in its α-amino group bind with the glycosyltransferase and transfers the saccharide molecule to the Nucleophilic group. Arginine binds with N- acetyl glucosamine and modifies its structure(Figure 2).

Figure 1

Figure 2

Step-by-step solution

Arginine residue

Arginineα-amino group consists of nucleophiles and is ready to bond with glycosyltransferase enzyme and transfer the saccharides.

N- acetyl glucosamine (GlcNAc) group binds with an arginine residue

N- acetyl glucosamine binds with the α-amino group of arginine containing the nucleophilic group and is involved in the structure change. It was shown in the diagram.

Arginine reacts with glycosyltransferase and modified its structure.