Question

A growth factor that acts through a receptor tyrosine kinase stimulates cell division. Predict the effect of a viral protein that inhibits the corresponding protein tyrosine phosphatase.

Short answer

The effect of a viral protein that inhibits the corresponding protein tyrosine phosphatase would be uncontrolled growth and division of cells

Step-by-step solution

Concept Introduction

Tyrosine kinasesplay a key role in the signaling pathwaythat leads to cell proliferation, differentiation, migration, metabolism, and programmed cell death.Tyrosine kinases are a group of enzymes that use ATP to catalyze the phosphorylation of specific tyrosine residues in target proteins

Effect of the viral Protein

Tyrosine phosphatase removes the phosphate group from tyrosine, while Tyrosine kinase adds one.

Inhibition of Tyrosine phosphatase would remove the control of cell proliferation, causing them to grow and divide uncontrollably; effectively making them cancer cells.

Therefore, division of cell and uncontrolled growth is the effect.