Question

Would the pancreatic hormone somatostatin require a receptor on the surface of or in the cytosol of a target cell?

Short answer

The pancreatic hormone somatostatin requires a cell-surface receptor.

Step-by-step solution

Concept Introduction

Somatostatin is a polypeptide that blocks the function of pancreatic and gastrointestinal hormones.Somatostatin comes in two forms: one with 14 amino acids and the other with 28 amino acids.

Requirement of a Receptor

For a hormone to enter the cytosol of a target cell, it needs to be lipid-soluble to pass through the membrane of the cell. However, somatostatin is not lipid-soluble and therefore requires a cell-surface receptor.

Therefore, a cell-surface receptor is required for somatostatin hormone..