Question

List the enzymes of amino acid metabolism in which channeling occurs.

Short answer

The enzymes of amino acid metabolism where channeling takes place are protease, amylase, glutaminase, and α-ketoglutarate.

Step-by-step solution

Channeling.

Channeling is the word used to describe the phenomenon when the product of two processes is transmitted directly from one enzyme’s active site to another.

Glutaminase hydrolyzation.

The major subunit of the enzyme catalyzes reactions, while the tiny subunit of the enzyme is a glutaminase that hydrolyzes glutamine. Glutamine is hydrolyzed to glutamate and ammonia. The ammonia is produced and moves by channeling, where it reacts with α-ketoglutarate.