Chapter 7: Problem 26
Are sister chromatid exchanges effective in producing genetic variability in an individual? in the offspring of individuals?
Chapter 7: Problem 26
Are sister chromatid exchanges effective in producing genetic variability in an individual? in the offspring of individuals?
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Get started for freeReview the Chapter Concepts list on page \(136 .\) Most of these center on the process of crossing over between linked genes. Write a short essay that discusses how crossing over can be detected and how the resultant data provide the basis of chromosome mapping.
In Drosophila, a cross was made between females expressing the three X-linked recessive traits, scute bristles \((s c),\) sable body \((s)\) and vermilion eyes ( \(v\) ), and wild-type males. All females were wild type in the \(\mathrm{F}_{1}\), while all males expressed all three mutant traits. The cross was carried to the \(\mathrm{F}_{2}\) generation and 1000 offspring were counted, with the results shown in the following table. No determination of sex was made in the \(\mathrm{F}_{2}\) data. (a) Using proper nomenclature, determine the genotypes of the \(\mathrm{P}_{1}\) and \(F_{1}\) parents. (b) Determine the sequence of the three genes and the map distance between them. (c) Are there more or fewer double crossovers than expected? (d) Calculate the coefficient of coincidence; does this represent positive or negative interference?
Phenotypically wild \(\mathrm{F}_{1}\) female Drosophila, whose mothers had light eyes (It) and fathers had straw (stw) bristles, produced the following offspring when crossed with homozygous light-straw males:$$\begin{array}{lc} \text { Phenotype } & \text { Number } \\ \hline \text { light-straw } & 22 \\ \text { wild } & 18 \\ \text { light } & 990 \\ \text { straw } & \frac{970}{2000} \end{array}$$ Compute the map distance between the light and straw loci.
Explain why restriction fragment length polymorphisms and microsatellites are important landmarks for mapping purposes.
Colored aleurone in the kernels of corn is due to the dominant allele \(R\). The recessive allele \(r,\) when homozygous, produces colorless aleurone. The plant color (not kernel color) is controlled by another gene with two alleles, \(Y\) and \(y\). The dominant \(Y\) allele results in green color, whereas the homozygous presence of the recessive \(y\) allele causes the plant to appear yellow. In a testross between a plant of unknown genotype and phenotype and a plant that is homozygous recessive for both traits, the following progeny were obtained: colored, green 88 colored, yellow 12 colorless, green 8 colorless, yellow 92 Explain how these results were obtained by determining the exact genotype and phenotype of the unknown plant, including the precise association of the two genes on the homologs (i.e., the arrangement).
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