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In a population of cattle, the following color distribution was noted: \(36 \%\) red \((R R), 48 \%\) roan \((R r),\) and \(16 \%\) white \((r r) .\) Is this population in a Hardy-Weinberg equilibrium? What will be the distribution of genotypes in the next generation if the HardyWeinberg assumptions are met?

Short Answer

Expert verified
Based on the given observed genotype frequencies and calculated expected genotype frequencies, determine if the population of cattle is in Hardy-Weinberg equilibrium and predict the distribution of genotypes in the next generation.

Step by step solution

01

1. Determine observed genotype frequencies

The exercise provides us with the observed genotype frequencies in the population: - Red (RR): \(36\%\) - Roan (Rr): \(48\%\) - White (rr): \(16\%\)
02

2. Calculate allele frequencies

We can use these observed genotype frequencies to calculate the frequency of each allele (R and r) in the population by applying the formula: \(p = \frac{2n(RR) + n(Rr)}{2n}\) (frequency of R) \(q = \frac{2n(rr) + n(Rr)}{2n}\) (frequency of r), where n is the total number of individuals in the population. Let's plug in the observed genotype frequencies: \(p = \frac{2(0.36) + 0.48}{2} = \frac{1.2}{2} = 0.6\) \(q = \frac{2(0.16) + 0.48}{2} = \frac{0.8}{2} = 0.4\) This means \(60\%\) of the alleles in the population are R and \(40\%\) are r.
03

3. Calculate expected genotype frequencies

Using the Hardy-Weinberg principle, we can determine the expected frequency of each genotype as follows: \(RR = p^2\) (Expected frequency of RR) \(Rr = 2pq\) (Expected frequency of Rr) \(rr = q^2\) (Expected frequency of rr) Plug in the allele frequencies we calculated above: \(RR = (0.6)^2 = 0.36\) \(Rr = 2(0.6)(0.4) = 0.48\) \(rr = (0.4)^2 = 0.16\)
04

4. Compare observed and expected genotype frequencies

Now, we can compare the expected frequencies we calculated above with the observed frequencies we were given to determine if the population is in Hardy-Weinberg equilibrium: Observed: - Red (RR): \(36\%\) - Roan (Rr): \(48\%\) - White (rr): \(16\%\) Expected (based on Hardy-Weinberg equilibrium): - Red (RR): \(36\%\) - Roan (Rr): \(48\%\) - White (rr): \(16\%\) The observed and expected genotype frequencies are the same, so the population is in Hardy-Weinberg equilibrium.
05

5. Predict genotype distribution in the next generation

If the population remains in Hardy-Weinberg equilibrium, then the frequencies of the genotypes will remain constant from generation to generation, and the distribution will be the same in the next generation: - Red (RR): \(36\%\) - Roan (Rr): \(48\%\) - White (rr): \(16\%\)

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Most popular questions from this chapter

What genetic changes take place during speciation?

Population geneticists study changes in the nature and amount of genetic variation in populations, the distribution of different genotypes, and how forces such as selection and drift act on genetic variation to bring about evolutionary change in populations and the formation of new species. From the explanation given in the chapter, what answers would you propose to the following fundamental questions? (a) How do we know how much genetic variation is in a population? (b) How do geneticists detect the presence of genetic variation as different alleles in a population? (c) How do we know whether the genetic structure of a population is static or dynamic? (d) How do we know when populations have diverged to the point that they form two different species? (e) How do we know the age of the last common ancestor shared by two species?

Consider a population in which the frequency of allele \(A\) is \(p=0.7\) and the frequency of allele \(a\) is \(q=0.3,\) and where the alleles are codominant. What will be the allele frequencies after one generation if the following occurs? (a) \(w_{A A}=1, w_{A a}=0.9,\) and \(w_{a a}=0.8\) (b) \(w_{A A}=1, w_{A a}=0.95,\) and \(w_{a a}=0.9\) (c) \(w_{A A}=1, w_{A a}=0.99, w_{a a}=0.98\) (d) \(w_{A A}=0.8, w_{A a}=1, w_{a a}=0.8\)

A certain form of albinism in humans is recessive and autosomal. Assume that \(1 \%\) of the individuals in a given population are albino. Assuming that the population is in Hardy-Weinberg equilibrium, what percentage of the individuals in this population is expected to be heterozygous?

The use of nucleotide sequence data to measure genetic variability is complicated by the fact that the genes of higher eukaryotes are complex in organization and contain \(5^{\prime}\) and \(3^{\prime}\) flanking regions as well as introns. Researchers have compared the nucleotide sequence of two cloned alleles of the \(\gamma\) -globin gene from a single individual and found a variation of 1 percent. Those differences include 13 substitutions of one nucleotide for another and 3 short DNA segments that have been inserted in one allele or deleted in the other. None of the changes takes place in the gene's exons (coding regions). Why do you think this is so, and should it change our concept of genetic variation?

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