Chapter 16: Problem 10
A genetic variant of the retinoblastoma protein, called PSM-RB (phosphorylation site mutated \(\mathrm{RB}\) ), is not able to be phosphorylated by the action of CDK4/cyclin D1 complex. Explain why PSM-RB is said to have a constitutive growth-suppressing action on the cell cycle.
Short Answer
Step by step solution
Key Concepts
These are the key concepts you need to understand to accurately answer the question.