Chapter 7: Problem 3
Describe the cytological observation that suggests that crossing over occurs during the first meiotic prophase.
Chapter 7: Problem 3
Describe the cytological observation that suggests that crossing over occurs during the first meiotic prophase.
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In this chapter, we focused on linkage, chromosomal mapping, and many associated phenomena. In the process, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions? (a) How was it established experimentally that the frequency of recombination (crossing over) between two genes is related to the distance between them along the chromosome? (b) How do we know that specific genes are linked on a single chromosome, in contrast to being located on separate chromosomes? (c) How do we know that crossing over results from a physical exchange between chromatids? (d) How do we know that sister chromatids undergo recombination during mitosis?
Review the Chapter Concepts list on p. \(121 .\) Most of these center on the process of crossing over between linked genes. Write a short essay that discusses how crossing over can be detected and how the resultant data provide the basis of chromosome mapping.
Why is a 50 percent recovery of single-crossover products the upper limit, even when crossing over always occurs between two linked genes?
Two different female Drosophila were isolated, each heterozygousfor the autosomally linked genes black body (b), dachs tarsus (d), and curved wings (c). These genes are in the order \(d-b-c\), with \(b\) closer to \(d\) than to \(c .\) Shown in the following table is the genotypic arrangement for each female, along with the various gametes formed by both. Identify which categories are noncrossovers (NCO), single crossovers (SCO), and double crossovers (DCO) in each case. Then, indicate the relative frequency with which each will be produced.
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