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Inversions are said to "suppress crossing over." Is this ter. minology technically correct? If not, restate the description accurately.

Short Answer

Expert verified
Answer: Inversions can reduce or prevent crossing over in the affected chromosomal regions.

Step by step solution

01

Understanding Inversions

Inversions are chromosomal mutations in which a segment of a chromosome is reversed end to end. An inversion occurs when a chromosome breaks in two places and the resulting piece of the chromosome is reinserted in the opposite orientation.
02

Understanding Crossing Over

Crossing over is a process that occurs during meiosis, where homologous chromosomes (two chromosomes having the same genes at the same loci but can have different alleles) exchange segments by breaking and rejoining each other. It results in a recombinant chromosome with a different combination of alleles than the parent chromosomes. Crossing over increases genetic diversity within a population.
03

The Impact of Inversions on Crossing Over

When an inversion occurs in one of the homologous chromosomes, the corresponding segments may not align properly during meiosis. As a result, the exchange of genetic material through crossover becomes difficult, if not impossible, because the break points required for exchange do not match. In other words, the inversion suppresses crossing over.
04

Evaluating the Terminology

While the term "Inversions suppress crossing over" is generally understandable, it may not be technically precise. A more accurate description could be: "Inversions can reduce or prevent crossing over in the affected chromosomal regions." This description acknowledges that inversions can have varying degrees of impact on crossing over, rather than suggesting that they always completely suppress it. Additionally, it clarifies that the suppression of crossing over is specific to the affected regions of chromosomes and not a complete suppression across all regions.

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Most popular questions from this chapter

Why do human monosomics most often fail to survive prenatal development?

Define these pairs of terms, and distinguish between them. aneuploidy/euploidy monosomy/trisomy Patau syndrome/Edwards syndrome autopolyploidy/allopolyploidy autotetraploid/amphidiploid paracentric inversion/pericentric inversion

A boy with Klinefelter syndrome \((47, \mathrm{XXY})\) is born to a mother who is phenotypically normal and a father who has the X-linked skin condition called anhidrotic ectodermal dysplasia. The mother's skin is completely normal with no signs of the skin abnormality. In contrast, her son has patches of normal skin and patches of abnormal skin. (a) Which parent contributed the abnormal gamete? (b) Using the appropriate genetic terminology, describe the meiotic mistake that occurred. Be sure to indicate in which division the mistake occurred. (c) Using the appropriate genetic terminology, explain the son's skin phenotype.

In this chapter, we focused on chromosomal mutations resulting from a change in number or arrangement of chromosomes. In our discussions, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions? (a) How do we know that the extra chromosome causing Down syndrome is usually maternal in origin? (b) How do we know that human aneuploidy for each of the 22 autosomes occurs at conception, even though most often human aneuploids do not survive embryonic or fetal development and thus are never observed at birth? (c) How do we know that specific mutant phenotypes are due to changes in chromosome number or structure? (d) How do we know that the mutant Bar-eye phenotype in Drosophila is due to a duplicated gene region rather than to a change in the nucleotide sequence of a gene?

In a human genetic study, a family with five phenotypically normal children was investigated. Two children were "homozy. gous" for a Robertsonian translocation between chromosomes 19 and 20 (they contained two identical copies of the fused chromosome). They have only 44 chromosomes but a complete genetic complement. Three of the children were "heterozygous" for the translocation and contained 45 chromosomes, with one translocated chromosome plus a normal copy of both chromosomes 19 and \(20 .\) Two other pregnancies resulted in stillbirths. It was later discovered that the parents were first cousins. Based on this information, determine the chromosome compositions of the parents. What led to the stillbirths? Why was the discovery that the parents were first cousins a key piece of information in understanding the genetics of this family?

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