Chapter 5: Problem 4
Distinguish between the concepts of sex determination and sexual differentiation.
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Key Concepts
These are the key concepts you need to understand to accurately answer the question.
Chapter 5: Problem 4
Distinguish between the concepts of sex determination and sexual differentiation.
These are the key concepts you need to understand to accurately answer the question.
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Get started for freeThe genes encoding the red-and green-color-detecting proteins of the human eye are located next to one another on the X chromosome and probably evolved from a common ancestral pigment gene. The two proteins demonstrate 76 percent homology in their amino acid sequences. A normal-visioned woman with both genes on each of her two X chromosomes has a redcolor-blind son who was shown to have one copy of the greendetecting gene and no copies of the red-detecting gene. Devise an explanation for these observations at the chromosomal level (involving meiosis).
In this chapter, we have focused on sex differentiation, sex chromosomes, and
genetic mechanisms involved in sex determination. At the same time, we found
many opportunities to consider the methods and reasoning by which much of this
information was acquired. From the explanations given in the chapter, you
should answer the following fundamental questions:
(a) How do we know that in humans the X chromosomes play no role in sex
determination, while the Y chromosome causes maleness and its absence causes
femaleness?
(b) How did we originally (in the late 1940 s) analyze the sex ratio at
conception in humans, and how has our approach to studying this issue changed
in
An attached-X female fly, XXY (see the Insights and Solutions box), expresses the recessive X-linked white-eye phenotype. It is crossed to a male fly that expresses the X-linked recessive miniature wing phenotype. Determine the outcome of this cross in terms of sex, eye color, and wing size of the offspring.
How do mammals, including humans, solve the "dosage problem" caused by the
presence of an
Cat breeders are aware that kittens expressing the X-linked calico coat pattern and tortoiseshell pattern (Figure 5.6 ) are almost invariably females. Why?
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