Chapter 3: Problem 11
Distinguish between homozygosity and heterozygosity.
Chapter 3: Problem 11
Distinguish between homozygosity and heterozygosity.
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Get started for freeTo assess Mendel's law of segregation using tomatoes, a true- breeding tall variety (SS) is crossed with a true-breeding short variety \((s s) .\) The heterozygous tall plants \((S s)\) were crossed to produce the two sets of \(\mathrm{F}_{2}\) data as follows: $$\begin{array}{cc} \text { Set I } & \text { Set II } \\ 30 \text { tall } & 300 \text { tall } \\ 5 \text { short } & 50 \text { short } \end{array}$$ (a) Using chi-square analysis, analyze the results for both datasets. Calculate \(\chi^{2}\) values, and estimate the \(p\) values in both cases. (b) From the analysis in part (a), what can you conclude about the importance of generating large datasets in experimental settings?
A geneticist, in assessing data that fell into two phenotypic classes, observed values of \(250: 150 .\) He decided to perform chi- square analysis using two different null hypotheses: (a) the data fit a 3: 1 ratio; and (b) the data fit a 1: 1 ratio. Calculate the \(\chi^{2}\) values for each hypothesis. What can you conclude about each hypothesis?
The basis for rejecting any null hypothesis is arbitrary. The researcher can set more or less stringent standards by deciding to raise or lower the critical \(p\) value. Would the use of a standard of \(p=0.10\) be more or less stringent in failing to reject the null hypothesis? Explain.
When working out genetics problems in this and succeeding chapters, always assume that members of the \(P_{1}\) generation are homozygous, unless the information or data you are given require you to do otherwise In this chapter, we focused on the Mendelian postulates, probability, and pedigree analysis. We also considered some of the methods and reasoning by which these ideas, concepts, and techniques were developed. On the basis of these discussions, what answers would you propose to the following questions: (a) How was Mendel able to derive postulates concerning the behavior of "unit factors" during gamete formation, when he could not directly observe them? (b) How do we know whether an organism expressing a dominant trait is homozygous or heterozygous? (c) In analyzing genetic data, how do we know whether deviation from the expected ratio is due to chance rather than to another, independent factor? (d) since experimental crosses are not performed in humans, how do we know how traits are inherited?
Two true-breeding pea plants are crossed. One parent is round, terminal, violet, constricted, while the other expresses the contrasting phenotypes of wrinkled, axial, white, full. The four pairs of contrasting traits are controlled by four genes, each located on a separate chromosome. In the \(F_{1}\) generation, only round, axial, violet, and full are expressed. In the \(\mathrm{F}_{2}\) generation, all possible combinations of these traits are expressed in ratios consistent with Mendelian inheritance. (a) What conclusion can you draw about the inheritance of these traits based on the \(\mathrm{F}_{1}\) results? (b) Which phenotype appears most frequently in the \(\mathrm{F}_{2}\) results? Write a mathematical expression that predicts the frequency of occurrence of this phenotype. (c) Which \(\mathrm{F}_{2}\) phenotype is expected to occur least frequently? Write a mathematical expression that predicts this frequency. (d) How often is either \(P_{1}\), phenotype likely to occur in the \(F_{2}\) generation? (e) If the \(F_{1}\) plant is testcrossed, how many different phenotypes will be produced?
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