Chapter 21: Problem 26
What are the two groups of reproductive isolating mechanisms? Which of these is regarded as more efficient, and why?
Chapter 21: Problem 26
What are the two groups of reproductive isolating mechanisms? Which of these is regarded as more efficient, and why?
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Get started for freeRecent reconstructions of evolutionary history are often dependent on assigning divergence in terms of changes in amino acid or nucleotide sequences. For example, a comparison of cytochrome c shows 10 amino acid differences between humans and dogs, 24 differences between humans and moths, and 38 differences between humans and yeast. Such data provide no information as to the absolute times of divergence for humans, dogs, moths, and yeast. How might one calibrate the molecular clock to an absolute time clock? What problems might one encounter in such a calibration?
One of the first Mendelian traits identified in humans was a dominant condition known as brachydactyly. This gene causes an abnormal shortening of the fingers or toes (or both). At the time, some researchers thought that the dominant trait would spread until 75 percent of the population would be affected (because the phenotypic ratio of dominant to recessive is 3: 1 ). Show that the reasoning was incorrect.
ConsiderapopulationinwhichthefrequencyofalleleAisp \(=0.7\) and thefrequencyofalleleais \(q=0.3\), andwheretheallelesarecodominant. What will be the allele frequencies after one generation if the following occurs? (a) \(w_{A A}=1, w_{A a}=0.9, w_{a a}=0.8\) (b) \(w_{A A}=1, w_{A a}=0.95, w_{a a}=0.9\) (c) \(w_{A A}=1, w_{A a}=0.99, w_{a a}=0.98\) (d) \(w_{A A}=0.8, w_{A a}=1, w_{a a}=0.8\)
Price et al. \([(1999) . \text { J. Bacteriol. } 181: 2358-2362]\) conducted a genetic study of the toxin transport protein (PA) of Bacillus anthracis, the bacterium that causes anthrax in humans. Within the 2294 -nucleotide gene in 26 strains they identified five point mutations- two missense and three synonyms-among different isolates. Necropsy samples from an anthrax outbreak in 1979 revealed a novel missense mutation and five unique nucleotide changes among ten victims. The authors concluded that these data indicate little or no horizontal transfer between different B. anthracis strains. (a) Which types of nucleotide changes (missense or synonyms) cause amino acid changes? (b) What is meant by "horizontal transfer"? (c) On what basis did the authors conclude that evidence of horizontal transfer is absent from their data?
In a population where only the total number of individuals wit the dominant phenotype is known, how can you calculate th percentage of carriers and homozygous recessives?
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