Chapter 20: Problem 10
List as many human traits as you can that are likely to be under the control of a polygenic mode of inheritance.
Chapter 20: Problem 10
List as many human traits as you can that are likely to be under the control of a polygenic mode of inheritance.
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Get started for freeIn an assessment of learning in Drosophila, flies were trained to avoid certain olfactory cues. In one population, a mean of 8.5 trials was required. A subgroup of this parental population that was trained most quickly (mean \(=6.0\) ) was interbred, and their progeny were examined. These flies demonstrated a mean training value of \(7.5 .\) Calculate realized heritability for olfactory learning in Drosophila.
While most quantitative traits display continuous variation, there are others referred to as "threshold traits" that are distin- guished by having a small number of discrete phenotypic classes. For example, Type 2 diabetes (adult-onset diabetes) is considered to be a polygenic trait, but demonstrates only two phenotypic classes: individuals who develop the disease and those who do not. Theorize how a threshold trait such as Type 2 diabetes may be under the control of many polygenes, but express a limited number of phenotypes.
A dark-red strain and a white strain of wheat are crossed and produce an intermediate, medium-red \(\mathrm{F}_{1}\). When the \(\mathrm{F}_{1}\) plants are interbred, an \(\mathrm{F}_{2}\) generation is produced in a ratio of 1 dark-red: 4 medium-dark-red: 6 medium-red: 4 light-red: 1 white, Further crosses reveal that the dark-red and white \(\mathrm{F}_{2}\) plants are true breeding. (a) Based on the ratios in the \(\mathrm{F}_{2}\) population, how many genes are involved in the production of color? (b) How many additive alleles are needed to produce each possible phenotype? (c) Assign symhols to these alleles and list pnssible genotypes that give rise to the medium-red and light-red phenotypes. (d) Predict the outcome of the \(F_{1}\) and \(F_{2}\) generations in a cross between a true-breeding medium-red plant and a white plant.
A strain of plants has a mean height of \(24 \mathrm{cm} .\) A second strain of the same species from a different geographical region also has a mean height of \(24 \mathrm{cm}\). When plants from the two strains are crossed together, the \(F_{1}\) plants are the same height as the parent plants. However, the \(\mathrm{F}_{2}\) generation shows a wide range of heights; the majority are like the \(P_{1}\) and \(F_{1}\) plants, but approximately 4 of 1000 are only $12 \mathrm{cm}\( high, and about 4 of 1000 are \)36 \mathrm{cm}$ high. (a) What mode of inheritance is occurring here? (b) How many gene pairs are involved? (c) How much does each gene contribute to plant height? (d) Indicate one possible set of genotypes for the original \(\mathrm{P}_{1}\) parents and the \(\mathrm{F}_{1}\) plants that could account for these results. (e) Indicate three possible genotypes that could account for \(\mathrm{F}_{2}\) plants that are \(18 \mathrm{cm}\) high and three that account for \(\mathrm{F}_{2}\) plants that are \(33 \mathrm{cm}\) high.
What kind of heritability estimates (broad sense or narrow sense) are obtained from human twin studies?
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