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If the analysis of DNA from two different microorganisms demonstrated very similar base compositions, are the DNA sequences of the two organisms also nearly identical?

Short Answer

Expert verified
Explain your answer. Answer: No, we cannot conclude that two microorganisms with very similar base compositions have nearly identical DNA sequences. Even if the proportion of A, T, C, and G is the same in both organisms, they can still have completely different DNA sequences. This is because the DNA sequence is determined by the specific order in which these nucleotide bases are arranged. To determine how similar their DNA sequences are, more information or comparison at the gene and regulatory element levels would be required.

Step by step solution

01

Understand Base Compositions and DNA Sequences

Base composition refers to the proportion of the four nucleotides (adenine [A], thymine [T], cytosine [C], and guanine [G]) in a DNA molecule. DNA sequence, on the other hand, refers to the specific order in which these nucleotides are arranged in the DNA molecule.
02

Compare base compositions

In this exercise, we are given that the base compositions of the DNA from two different microorganisms are very similar. This means that the percentages of A, T, C, and G in their DNA are nearly the same. However, having a similar base composition does not provide enough information about the actual arrangement of these bases in the DNA sequence.
03

Determine the relationship between base composition and DNA sequence

It is important to note that similar base compositions do not necessarily imply similar DNA sequences. Even if the proportion of A, T, C, and G is the same in both organisms, they can still have completely different DNA sequences. This is because the DNA sequence is determined by the specific order in which these nucleotide bases are arranged. If two organisms have similar base compositions but different DNA sequences, it means that their genes and regulatory elements may differ, potentially leading to differences in traits and functions.
04

Apply the concept to the given problem

Since the base composition only reflects the overall proportions of the nucleotide bases in the DNA, instead of their arrangement, it is not enough to conclude that the DNA sequences of the two organisms are nearly identical simply based on their similar base compositions. To answer this question, we would need more information about the actual sequences of their DNA.
05

Conclusion

In conclusion, having very similar base compositions does not necessarily mean that the DNA sequences of the two organisms are also nearly identical. To determine how similar their DNA sequences are, more information or comparison at the gene and regulatory element levels would be required.

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Most popular questions from this chapter

Define and indicate the significance of (a) Okazaki fragments, (b) DNA ligase, and (c) primer RNA during DNA replication.

Several temperature-sensitive mutant strains of \(E .\) coli display the following characteristics. Predict what enzyme or function is being affected by each mutation. (a) Newly synthesized DNA contains many mismatched base pairs. (b) Okazaki fragments accumulate, and DNA synthesis is never completed. (c) No initiation occurs. (d) Synthesis is very slow. (e) Supercoiled strands remain after replication, which is never completed.

List and describe the function of the ten subunits constituting DNA polymerase III. Distinguish between the holoenzyme and the core enzyme.

Kornberg showed that nucleotides are added to the 3 '-end of each growing DNA strand. In what way does an exposed \(3^{\prime}\) - OH group participate in strand elongation?

In this chapter, we focused on how DNA is replicated and synthesized. In particular, we elucidated the general mechanism of replication and described how DNA is synthesized when it is copied. Based on your study of these topics, answer the following fundamental questions: (a) What is the experimental basis for concluding that DNA replicates semiconservatively in both bacteria and eukaryotes? (b) How was it demonstrated that DNA synthesis occurs under the direction of DNA polymerase III and not polymerase I? (c) How do we know that in vivo DNA synthesis occurs in the \(5^{\prime}\) to \(3^{\prime}\) direction? (d) How do we know that DNA synthesis is discontinuous on one of the two template strands? (e) What observations reveal that a "telomere problem" exists during eukaryotic DNA replication, and how did we learn of the solution to this problem?

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