Chapter 26: Problem 25
List the barriers that prevent interbreeding, and give an example of each.
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Key Concepts
These are the key concepts you need to understand to accurately answer the question.
Chapter 26: Problem 25
List the barriers that prevent interbreeding, and give an example of each.
These are the key concepts you need to understand to accurately answer the question.
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Get started for freeConsider a population in which the frequency of allele \(A\) is \(p=0.7\) and the frequency of allele \(a\) is \(q=0.3,\) and where the alleles are codominant. What will be the allele frequencies after one generation if the following occurs? (a) \(w_{\mu}=1, w_{A a}=0.9, w_{a a}=0.8\) (b) \(w_{\mu}=1, w_{A a}=0.95, w_{a a}=0.9\) (c) \(w_{\mu}=1, w_{h a}=0.99, w_{a a}=0.98\) (d) \(w_{\mu}=0.8, w_{A a}=1, w_{a a}=0.8\)
The use of nucleotide sequence data to measure genetic vari- ability is complicated by the fact that the genes of many eukaryotes are complex in organization and contain \(5^{\prime}\) and \(3^{\prime}\) flanking regions as well as introns. Researchers have compared the nucleotide sequence of two cloned alleles of the \(\gamma\) -globin gene from a single individual and found a variation of 1 percent. Those differences include 13 substitutions of one nucle- otide for another and three short DNA segments that have been inserted in one allele or deleted in the other. None of the changes takes place in the gene's exons (coding regions). Why do you think this is so, and should it change our concept of genetic variation?
Recent reconstructions of evolutionary history are often dependent on assigning divergence in terms of changes in amino acid or nucleotide sequences. For example, a comparison of cytochrome c shows 10 amino acid differences between humans and dogs, 24 differences between humans and moths, and 38 differences between humans and yeast. Such data provide no information as to the absolute times of divergence for humans, dogs, moths, and yeast. How might one calibrate the molecular clock to an absolute time clock? What problems might one encounter in such a calibration?
A form of dwarfism known as Ellis-van Creveld syndrome was first discovered in the late 1930 s, when Richard Ellis and Simon van Creveld shared a train compartment on the way to a pediatrics meeting. In the course of conversation, they discovered that they each had a patient with this syndrome. They published a description of the syndrome in \(1940 .\) Affected individuals have a short-limbed form of dwarfism and often have defects of the lips and teeth, and polydactyly (extra fingers). The largest pedigree for the condition was reported in an Old Order Amish population in eastern Pennsylvania by Victor McKusick and his colleagues \((1964) .\) In that community, about 5 per 1000 births are affected, and in the population of 8000 , the observed frequency is 2 per 1000\. All affected individuals have unaffected parents, and all affected cases can trace their ancestry to Samuel King and his wife, who arrived in the area in \(1774 .\) It is known that neither King nor his wife was affected with the disorder. There are no cases of the disorder in other Amish communities, such as those in Ohio or Indiana. (a) From the information provided, derive the most likely mode of inheritance of this disorder. Using the Hardy-Weinberg law, calculate the frequency of the mutant allele in the population and the frequency of heterozygotes, assuming Hardy- Weinberg conditions. (b) What is the most likely explanation for the high frequency of the disorder in the Pennsylvania Amish community and its absence in other Amish communities?
If 4 percent of a population in equilibrium expresses a recessive trait, what is the probability that the offspring of two individuals who do not express the trait will express it?
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