Chapter 23: Problem 3
Define the following: (a) polygenic, (b) additive alleles, (c) correlation, (d) monozygotic and dizygotic twins, (e) heritability, (f) \(\mathrm{QTL},\) and \((\mathrm{g})\) continuous variation.
Chapter 23: Problem 3
Define the following: (a) polygenic, (b) additive alleles, (c) correlation, (d) monozygotic and dizygotic twins, (e) heritability, (f) \(\mathrm{QTL},\) and \((\mathrm{g})\) continuous variation.
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Get started for freeDescribe the value of using twins in the study of questions relating to the relative impact of heredity versus environment.
In this chapter, we focused on a mode of inheritance referred to as quantitative genetics, as well as many of the statistical parameters utilized to study quantitative traits. Along the way, we found opportunities to consider the methods and reasoning by which geneticists acquired much of their understanding of quantitative genetics. From the explanations given in the chapter, what answers would you propose to the following fundamental questions: (a) How do we know that threshold traits are actually polygenic even though they may have as few as two discrete phenotypic classes? (b) How can we ascertain the number of polygenes involved in the inheritance of a quantitative trait?
Corn plants from a test plot are measured, and the distribution of heights at \(10-\mathrm{cm}\) intervals is recorded in the following table: $$\begin{array}{cc}\text { Height }(\mathrm{cm}) & \text { Plants (no.) } \\\100 & 20 \\\110 & 60 \\\120 & 90 \\\130 & 130 \\\140 & 180 \\\150 & 120 \\\160 & 70 \\\170 & 50 \\\180 & 40\end{array}$$ Calculate (a) the mean height, (b) the variance, (c) the standard deviation, and (d) the standard error of the mean. Plot a rough graph of plant height against frequency. Do the values represent a normal distribution? Based on your calculations, how would you assess the variation within this population?
Type A1B brachydactyly (short middle phalanges) is a genetically determined trait that maps to the short arm of chromosome 5 in humans. If you classify individuals as either having or not having brachydactyly, the trait appears to follow a single-locus, incompletely dominant pattern of inheritance. However, if one examines the fingers and toes of affected individuals, one sees a range of expression from extremely short to only slightly short. What might cause such variation in the expression of brachydactyly?
An inbred strain of plants has a mean height of \(24 \mathrm{cm} .\) A second strain of the same species from a different geographical region also has a mean height of \(24 \mathrm{cm} .\) When plants from the two strains are crossed together, the \(\mathrm{F}_{1}\) plants are the same height as the parent plants. However, the \(\mathrm{F}_{2}\) generation shows a wide range of heights; the majority are like the \(P_{1}\) and \(F_{1}\) plants, but approximately 4 of 1000 are only \(12 \mathrm{cm}\) high and about 4 of 1000 are \(36 \mathrm{cm}\) high. (a) What mode of inheritance is occurring here? (b) How many gene pairs are involved? (c) How much does each gene contribute to plant height? (d) Indicate one possible set of genotypes for the original \(P_{1}\) parents and the \(\mathrm{F}_{1}\) plants that could account for these results. (e) Indicate three possible genotypes that could account for \(\mathrm{F}_{2}\) plants that are \(18 \mathrm{cm}\) high and three that account for \(\mathrm{F}_{2}\) plants that are \(33 \mathrm{cm}\) high.
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