Chapter 23: Problem 10
Describe the value of using twins in the study of questions relating to the relative impact of heredity versus environment.
Chapter 23: Problem 10
Describe the value of using twins in the study of questions relating to the relative impact of heredity versus environment.
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Get started for freeStudents in a genetics laboratory began an experiment in an attempt to increase heat tolerance in two strains of Drosophila melanogaster. One strain was trapped from the wild six weeks before the experiment was to begin; the other was obtained from a Drosophila repository at a university laboratory. In which strain would you expect to see the most rapid and extensive response to heat-tolerance selection, and why?
Osteochondrosis (OC) is a developmental orthopedic disorder in young, growing horses, where irregular bone formation in the joints leads to necrotic areas, resulting in chronic or recurrent lameness. Incidence of OC varies considerably among breeds, and displays a multifactorial mode of inheritance. The incidence of \(\mathrm{OC}\) is rising in the population of race horses. Discuss the reasons why the incidence of OC might be rising, and describe what can be done to detect OC susceptibility in horses with the help of QTL analysis.
Corn plants from a test plot are measured, and the distribution of heights at \(10-\mathrm{cm}\) intervals is recorded in the following table: $$\begin{array}{cc}\text { Height }(\mathrm{cm}) & \text { Plants (no.) } \\\100 & 20 \\\110 & 60 \\\120 & 90 \\\130 & 130 \\\140 & 180 \\\150 & 120 \\\160 & 70 \\\170 & 50 \\\180 & 40\end{array}$$ Calculate (a) the mean height, (b) the variance, (c) the standard deviation, and (d) the standard error of the mean. Plot a rough graph of plant height against frequency. Do the values represent a normal distribution? Based on your calculations, how would you assess the variation within this population?
The mean and variance of plant height of two highly inbred strains \(\left(P_{1} \text { and } P_{2}\right)\) and their progeny \(\left(F_{1} \text { and } F_{2}\right)\) are shown here. $$\begin{array}{ccc}\text { Strain } & \text { Mean (cm) } & \text { Variance } \\\\\mathrm{P}_{1} & 34.2 & 4.2 \\\\\mathrm{P}_{2} & 55.3 & 3.8 \\\\\mathrm{F}_{1} & 44.2 & 5.6 \\\\\mathrm{F}_{2} & 46.3 & 10.3\end{array}$$ Calculate the broad-sense heritability \(\left(H^{2}\right)\) of plant height in this species.
Consider a true-breeding plant, \(A A B B C C\), crossed with another true- breeding plant, aabbcc, whose resulting offspring are AaBbCc. If you cross the \(\mathrm{F}_{1}\) generation, and independent assortment is operational, the expected fraction of offspring in each phenotypic class is given by the expression \(N ! / M !(N-M) !\) where \(N\) is the total number of alleles (six in this example) and \(M\) is the number of uppercase alleles. In a cross of \(A a B b C c \times A a B b C c,\) what proportion of the offspring would be expected to contain two uppercase alleles?
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