Chapter 22: Problem 4
An unapproved form of gene therapy, known as enhancement gene therapy, can create considerable ethical dilemmas. Why?
Chapter 22: Problem 4
An unapproved form of gene therapy, known as enhancement gene therapy, can create considerable ethical dilemmas. Why?
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Get started for freeIn this chapter, we focused on a number of interesting applications of genetic engineering, genomics, and biotechnology. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, what answers would you propose to the following fundamental questions: (a) What experimental evidence confirms that we have introduced a useful gene into a transgenic organism and that it performs as we anticipate? (b) How can we use DNA analysis to determine that a human fetus has sickle- cell anemia? (c) How can DNA microarray analysis be used to identify specific genes that are being expressed in a specific tissue? (d) How are GWAS carried out, and what information do they provide? (e) What are some of the technical reasons why gene therapy is difficult to carry out effectively?
Once DNA is separated on a gel, it is often desirable to gain some idea of its informational content. How might this be done?
Would you have your genome sequenced, if the price was affordable? Why or why not? If you answered yes, would you make your genome sequence publicly available? How might such information be misused?
There are more than 1000 cloned farm animals in the United States. In the near future, milk from cloned cows and their offspring (born naturally) may be available in supermarkets. These cloned animals have not been transgenically modified, and they are no different than identical twins. Should milk from such animals and their natural-born offspring be labeled as coming from cloned cows or their descendants? Why?
Sequencing the human genome and the development of microarray technology promise to improve our understanding of normal and abnormal cell behavior. How are microarrays dramatically changing our understanding of complex diseases such as cancer?
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