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(a) What are zygotic genes, and when are their gene products made? (b) What is the phenotype associated with zygotic gene mutations? (c) Does the maternal genotype contain zygotic genes?

Short Answer

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Answer: Zygotic genes are genes that are expressed in the zygote, the initial cell formed during fertilization in sexually reproducing organisms. These genes are significant in embryonic development as they are crucial for proper cell division, tissue formation, and overall growth and development of the organism. Mutations in zygotic genes can lead to a variety of phenotypes, including developmental abnormalities or even lethality in the embryo.

Step by step solution

01

Understanding zygotic genes

Zygotic genes are genes that are expressed in the zygote, which is the initial cell formed when two individual gametes (sperm and egg cells) fuse during fertilization in sexually reproducing organisms. The gene products of zygotic genes are made during the development of the embryo when the zygote undergoes cell division and differentiation.
02

Phenotype associated with zygotic gene mutations

Zygotic gene mutations can lead to a variety of phenotypes depending on the specific gene involved and the effect of the mutation. Generally, these mutations can result in developmental abnormalities, malformations, or even lethality in the embryo. This is because zygotic genes are crucial for proper cell division, tissue formation, and overall growth and development of the organism.
03

Presence of zygotic genes in the maternal genotype

Yes, the maternal genotype contains zygotic genes. A genotype refers to the complete set of genes present in an organism, including both maternal and paternal genes. Zygotic genes are present in both parental genotypes, and they are contributed to the zygote during fertilization. However, the expression or activation of zygotic genes in the developing embryo occurs independent of the maternal genotype.

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Most popular questions from this chapter

List the main classes of zygotic genes. What is the function of each class of these genes?

The identification and characterization of genes that control sex determination has been a focus of investigators working with \(C .\) elegans. As with Drosophila, sex in this organism is determined by the ratio of \(X\) chromosomes to sets of autosomes. A diploid wild-type male has one \(X\) chromosome and a diploid wild-type hermaphrodite has two X chromosomes. Many different mutations have been identified that affect sex determination. Loss- of-function mutations in a gene called her-1 cause an XO nematode to develop into a hermaphrodite and have no effect on \(\mathrm{XX}\) development. (That is, \(\mathrm{XX}\) nematodes are normal hermaphrodites.) In contrast, loss- offunction mutations in a gene called tra-I cause an XX nematode to develop into a male. Deduce the roles of these genes in wild-type sex determination from this information.

Carefully distinguish between the terms differentiation and determination. Which phenomenon occurs initially during development?

In this chapter, we have focused on large-scale as well as the inter- and intracellular events that take place during embryogenesis and the formation of adult structures. In particular, we discussed how the adult body plan is laid down by a cascade of gene expression, and the role of cell-cell communication in development. Based on your knowledge of these topics, answer several fundamental questions: (a) How do we know how many genes control development in an organism like Drosophila? (b) What experimental evidence demonstrates that molecular gradients in the egg control development? (c) How did we discover that selector genes specify which adult structures will be formed by body segments? (d) How did we learn about the levels of gene regulation involved in vulval development in \(C .\) elegans? (e) How do we know that eye formation in all animals is controlled by a binary switch gene?

(a) What are maternal-effect genes? (b) When are gene products from these genes made, and where are they located? (c) What aspects of development do maternal-effect genes control? (d) What is the phenotype of maternal-effect mutations?

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