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What is meant by a conditional mutation?

Short Answer

Expert verified
Answer: A conditional mutation is a genetic change that alters an organism's phenotype (observable characteristics) only under specific environmental conditions. An example of a conditional mutation is a mutation in bacteria that allows them to grow in the presence of an antibiotic. In the absence of the antibiotic, the bacteria exhibit a wild-type phenotype, but if the antibiotic is present, they show a mutant phenotype, surviving and growing despite the presence of the antibiotic.

Step by step solution

01

Define conditional mutation

Conditional mutations are genetic changes that alter an organism's phenotype (observable characteristics) only under specific environmental conditions. Under other conditions, the organism will exhibit a wild-type or normal phenotype.
02

Provide an example of a conditional mutation

For instance, let's consider a mutation in bacteria that allows them to grow in the presence of an antibiotic. If the bacteria are grown in an environment where there is no antibiotic present, they will exhibit a wild-type phenotype and show no change in their growth pattern. However, if the antibiotic is present, the bacteria will show a mutant phenotype by surviving and growing in the presence of the antibiotic. The mutated gene is expressed only under the specific environmental condition, hence it is a conditional mutation.

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Key Concepts

These are the key concepts you need to understand to accurately answer the question.

Genetic Mutation
Genetic mutations refer to changes in the DNA sequence of an organism. These changes can occur due to various reasons, such as errors during DNA replication or exposure to environmental factors like radiation. Genetic mutations can lead to changes in the structure and function of proteins, which can affect an organism's traits or functions. It's like altering the blueprint of a building, which can lead to changes in the building's final appearance or structure.

Mutations can be classified into different types:
  • Point mutations: These involve changes in a single nucleotide.
  • Insertions and deletions: These involve the addition or loss of one or more nucleotides.
  • Chromosomal mutations: These affect large segments of DNA or entire chromosomes.
Mutations can have beneficial, neutral, or harmful effects depending on where they occur and how they impact the organism. Some mutations provide advantages, such as antibiotic resistance in bacteria, while others can cause diseases.
Phenotype
A phenotype is the collection of an organism's observable characteristics or traits, such as eye color, height, or leaf shape in plants. These traits result from the interaction between the organism's genetic makeup or genotype and the environment in which it lives. In essence, the phenotype is the physical manifestation of the genotype in a specific environment.

Factors influencing phenotypes include:
  • Genetic factors: The specific genes inherited from parents.
  • Environmental factors: Conditions like temperature and nutrition that can influence how genes are expressed.
For example, the flower color of certain plants may change based on soil pH, even though the genetic information remains the same. Understanding phenotypes helps scientists and researchers study how genetic variations lead to different observable traits in organisms.
Environmental Conditions
Environmental conditions are external factors that influence the survival and expression of traits in organisms. These can include temperature, humidity, light, soil quality, availability of nutrients, and presence of other organisms. In the context of conditional mutations, environmental conditions determine whether the mutation will affect the phenotype of an organism.

Key influences of environmental conditions include:
  • Temperature: Some seeds germinate only at certain temperatures.
  • Availability of resources: The presence of nutrients and water affects growth rates.
  • Stress factors: Pollution or toxins may influence survival and trait expression.
Organisms adapt to their environment to optimize their survival and reproduction. Conditional mutations highlight how specific environmental triggers can unveil genetic changes, causing certain traits to manifest under particular circumstances. Understanding these relationships is crucial in fields like genetics, ecology, and evolutionary biology.

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Most popular questions from this chapter

Describe a tautomeric shift and how it may lead to a mutation.

A significant number of mutations in the \(H B B\) gene that cause human \(\beta\) -thalassemia occur within introns or in upstream noncoding sequences. Explain why mutations in these regions often lead to severe disease, although they may not directly alter the coding regions of the gene.

Presented here are hypothetical findings from studies of heterokaryons formed from seven human xeroderma pigmentosum cell strains: $$\begin{array}{lccccccc} & X P 1 & X P 2 & X P 3 & X P 4 & X P 5 & X P 6 & X P 7 \\ X P 1 & \- & & & & & & \\ X P 2 & \- & \- & & & & & \\ X P 3 & \- & \- & \- & & & & \\ X P 4 & \+ & \+ & \+ & \- & & & \\ X P S & \+ & \+ & \+ & \+ & \- & & \\ X P 6 & \+ & \+ & \+ & \+ & \- & \- & \\ X P 7 & \+ & \+ & \+ & \+ & \- & \- & - \end{array}$$ These data are measurements of the occurrence or nonoccur- rence of unscheduled DNA synthesis in the fused heterokaryon. None of the strains alone shows any unscheduled DNA synthesis. Which strains fall into the same complementation groups? How many different groups are revealed based on these data? What can we conclude about the genetic basis of XP from these data?

In maize, a \(D s\) or \(A c\) transposon can cause mutations in genes at or near the site of transposon insertion. It is possible for these elements to transpose away from their original site, causing a reversion of the mutant phenotype. In some cases, however, even more severe phenotypes appear, due to events at or near the mutant allele. What might be happening to the transposon or the nearby gene to create more severe mutations?

What genetic defects result in the disorder xeroderma pigmentosum (XP) in humans? How do these defects create the phenotypes associated with the disorder?

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