Chapter 15: Problem 7
Why are organisms that have a haploid life cycle valuable tools for mutagenesis studies?
Chapter 15: Problem 7
Why are organisms that have a haploid life cycle valuable tools for mutagenesis studies?
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Get started for freeIn this chapter, we focused on how gene mutations arise and how cells repair DNA damage. At the same time, we found opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, (a) How do we know that mutations occur spontaneously? (b) How do we know that certain chemicals and wavelengths of radiation induce mutations in DNA? (c) How do we know that DNA repair mechanisms detect and correct the majority of spontaneous and induced mutations?
Most mutations are thought to be deleterious. Why, then, is it reasonable to state that mutations are essential to the evolutionary process?
What is meant by a conditional mutation?
The initial discovery of IS elements in bacteria revealed the presence of an element upstream \(\left(5^{\prime}\right)\) of three genes controlling galactose metabolism. All three genes were affected simultaneously, although there was only one IS insertion. Offer an explanation as to why this might occur.
Why would a mutation in a mismatch repair gene lead to a mutator phenotype in a cell?
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