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Explain how the signaling molecules released by an embryonic cell can induce changes in a neighboring cell without entering the cell. (See Figures 11.15 and 11.16.)

Short Answer

Expert verified

Signaling molecules can induce changes in neighboring cells by binding with the receptors on these cells. It can trigger a signal transduction pathway that involves many molecules in the cells like secondary messengers and transcription factors. Finally, it affects the gene expression of the signal-receiving cells.

Step by step solution

01

Signaling molecules

Signaling molecules that are released by cells are very small and soluble molecules that are called ligands. These can trigger a signal transduction pathway in the neighboring cells by binding the receptors present on their membranes. A specific signal binds with a specific receptor.

02

Step 2: Signal transduction pathway

Cells can receive and process the signals released by other cells or the outer environment. For this purpose, they have receptors that are generally found as transmembrane proteins and transmit the message through a sequence of molecules to the internal signaling pathway.

03

Step 3: Signal transduction pathway in embryonic cells

Signals released by embryonic cells can initiate a signal transduction pathway that regulates the activity of genes in the nucleus of neighboring cells.

The signals make a phosphorylation cascade in the molecule switches and transcription factors that affect the gene expression of neighboring cells, thereby altering their activity.

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Most popular questions from this chapter

Which of the following statements about the DNA in one of your brain cells is true?

(A) Most of the DNA codes for protein.

(B) The majority of genes are likely to be transcribed.

(C) It is the same as the DNA in one of your liver cells.

(D) Each gene lies immediately adjacent to an enhancer.

Cell differentiation always involves

(A) transcription of the myoD gene.

(B) the movement of cells.

(C) the production of tissue-specific factors

(D) the selection loss of certain genes from the genome.

The p53 protein can activate genes involved in apoptosis. Review Concept 11.5, and discuss how mutations in genes coding for proteins that function in apoptosis could contribute to cancer.

The diagram below five genes, including their enhancers, from the genome of a certain species. Imagine that pink, blue, green, black, grey and dark blue activator proteins exist that can bind to the approximately colour-coded control elements in the enhancers of these genes.

(a) Draw an X above enhancer elements (of all the genes) that would have activators bound in a cell where only gene five is transcribed. Identify which coloured activators would be present.

(b) Draw a dot above all enhancer elements that would have activators bound in a cell where the green, blue, and yellow activators are present. Identify which gene(s) would be transcribed.

(c) Imagine that genes 1, 2, and 4 codes for nerve-specific proteins, and genes 3 and 5 are skin-specific. Identify which activators would have to be present in each cell type to ensure transcription of the appropriate genes.

Compare miRNAs and siRNAs, including their functions.

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