Question

How does negative feedback in thermoregulation differ from feedback inhibition in an enzyme-catalyzed biosynthetic process (see Figure 8.21)

Short answer

The negative feedback and feedback inhibition differ because the pathway's product in thermoregulation reduces pathway activity by decreasing the stimulus. However, in an enzyme-catalyzed biosynthetic process, the pathway product stops the pathway activity that manufactured it.

Step-by-step solution

Feedback inhibition

Feedback inhibition is used by cells to regulate metabolic enzyme activity by the inhibitory binding of its end product to an enzyme acting early in the metabolic pathway. The activity of an enzyme is suppressed or slows down, making new products altogether.

Negative feedback mechanisms

The negative feedback mechanism is a pathway stimulated by deviance in output and produces changes in the opposite direction of the initial deviation and maintains homeostasis. The negative feedback mechanism is a self-regulatory system and works to maintain relatively constant levels of output.

Thermoregulation

Thermoregulation is a mechanism that allows the maintenance of the internal body. Thus, it involves maintaining an optimal temperature for the action of enzymes in the body. Homeostasis regulates temperature that sustains a stable internal temperature to survive.

The homeostasis of the body utilizes negative feedback by generating sweat when the body produces a large amount of body heat.