Question

Calculate the dosages as indicated. Use the labels where provided. Inocor \(250 \mathrm{mg}\) in \(250 \mathrm{~mL}\) of \(0.9 \%\) NS to infuse at a rate of \(5 \mathrm{mcg} / \mathrm{kg} / \mathrm{min}\) is ordered for a client weighing 165 lb. Calculate the following: a. \(\mathrm{mcg} / \mathrm{min}\) b. \(\mathrm{mcg} / \mathrm{hr}\) c. \(\mathrm{mL} / \mathrm{hr}\)

Short answer

a) 374.2 mcg/min b) 22452 mcg/hr c) 22.45 mL/hr

Step-by-step solution

Convert Weight from Pounds to Kilograms

To convert the client's weight from pounds to kilograms, use the conversion factor: \(1 \text{ lb} = 0.453592 \text{ kg}\). Calculate the client's weight in kilograms: \[165 \text{ lb} \times 0.453592 \text{ kg/lb} = 74.84268 \text{ kg} \approx 74.84 \text{ kg}\].

Calculate Dosage in mcg/min

Use the dosage rate to find the total micrograms per minute. Multiply the client's weight in kilograms by the dosage rate: \[5 \text{ mcg/kg/min} \times 74.84 \text{ kg} = 374.2 \text{ mcg/min}\].

Calculate Dosage in mcg/hr

Convert the dosage from micrograms per minute to micrograms per hour by multiplying by the number of minutes in an hour (60):\[374.2 \text{ mcg/min} \times 60 \text{ min/hr} = 22452 \text{ mcg/hr}\].

Determine Concentration in mg/mL

Calculate the concentration of the Inocor solution. It is given as 250 mg in 250 mL, leading to:\[\frac{250 \text{ mg}}{250 \text{ mL}} = 1 \text{ mg/mL}\].

Convert Concentration to mcg/mL

Convert the concentration from mg/mL to mcg/mL knowing that \(1 \text{ mg} = 1000 \text{ mcg}\):\[1 \text{ mg/mL} = 1000 \text{ mcg/mL}\].

Calculate Flow Rate in mL/hr

Using the dosage in mcg/hr and the concentration of the solution, calculate the flow rate in mL/hr:\[\frac{22452 \text{ mcg/hr}}{1000 \text{ mcg/mL}} = 22.452 \text{ mL/hr} \approx 22.45 \text{ mL/hr}\].

Key concepts

Weight Conversion

When working on dosage calculations, it's often necessary to convert the weight of a patient from pounds to kilograms since medical dosages are typically based on weight in kilograms. The standard conversion factor is used here: 1 pound equals approximately 0.453592 kilograms. For a patient weighing 165 pounds, the conversion to kilograms would be:

• You multiply 165 pounds by 0.453592 to get approximately 74.84268 kilograms.
• Rounding, you find that the patient's weight is approximately 74.84 kilograms.

Understanding weight conversion is crucial for accurate medication dosages, as missteps here could lead to significant errors.

Medication Concentration

In medical settings, understanding the concentration of a medication is key. Concentration denotes the amount of medication present in a particular volume of solution. In this scenario, Inocor is mixed so that there are 250 mg in 250 mL of solution. This translates to a concentration of:

• 1 mg/mL, because 250 mg divided by 250 mL results in 1 mg/mL.

Furthermore, for easier calculations, it is often necessary to convert this concentration into mcg/mL, knowing 1 mg is equivalent to 1000 mcg:

• This results in a concentration of 1000 mcg/mL.

The understanding of medication concentration helps avoid errors in administering incorrect doses.

Flow Rate Calculation

To ensure correct administration of intravenous (IV) medications, calculating the proper flow rate is essential. Flow rate tells you how quickly the IV fluid is being administered.**Calculating Flow Rate:**Given the dosage in micrograms per hour and the concentration in micrograms per milliliter, we calculate flow rate as follows:

• From previous calculations, the dosage was found to be 22,452 mcg/hr.
• Using the concentration of 1000 mcg/mL, the flow rate in mL/hr is calculated as: \[\frac{22452 \, \text{mcg/hr}}{1000 \, \text{mcg/mL}} = 22.452 \, \text{mL/hr} \approx 22.45 \, \text{mL/hr}\]

Properly understanding flow rate calculations helps ensure the patient receives medicine at the correct rate, preventing under or overdosing.

Dosage Rate

The dosage rate refers to the quantity of medication a patient should receive per unit of time, frequently used in contexts such as mcg/kg/min or mcg/min. **Calculating Dosage Rate Ensurements:**

• The given parameter is 5 mcg/kg/min.
• Multiplying the weight (74.84 kg) by the dosage rate, gives 374.2 mcg/min, representing what the patient should receive each minute.
• This can be extended to hours, multiplying 374.2 mcg/min by 60 to receive 22,452 mcg/hr.

The understanding of dosage rate is a pivotal component in medication calculations as it ensures the proper amount of drug is administered over the specified time frame.