Question

Calculate the hourly dosage of heparin (units/hr). Order: 20,000 units of heparin in \(1 \mathrm{~L}\) of D5W to infuse at \(80 \mathrm{~mL} / \mathrm{hr}\).

Short answer

The hourly dosage of heparin is 1,600 units/hr.

Step-by-step solution

Determine the concentration of heparin

The concentration of heparin in the solution is given as 20,000 units in 1 liter (1,000 mL). We calculate the concentration by dividing the total units of heparin by the total volume of the solution:\[\text{Concentration} = \frac{20,000 \text{ units}}{1,000 \text{ mL}} = 20 \frac{\text{units}}{\text{mL}}\]

Calculate the hourly dosage

To find the hourly dosage, we need to multiply the concentration of heparin by the infusion rate. The infusion rate is given as 80 mL/hr:\[\text{Hourly dosage} = 20 \frac{\text{units}}{\text{mL}} \times 80 \, \text{mL/hr} = 1,600 \, \text{units/hr}\]

Key concepts

Understanding Heparin Infusion

Heparin is a blood-thinning medication often used in hospitals to prevent or treat blood clots. When administering heparin through an infusion, it is dissolved in a solution, such as D5W, which stands for 5% dextrose in water. This solution is then delivered intravenously over a set period, based on the prescribed dosage.
Nurses need to be precise when calculating the infusion rate, as incorrect dosages can lead to complications. Knowing how to determine the correct dosage per hour is crucial for patient safety. In this exercise, the order specifies 20,000 heparin units in 1 liter of D5W. This precision ensures a steady and appropriate infusion rate of 80 mL per hour, thus delivering the medication effectively.

• Heparin helps prevent clotting
• Infusion setup requires careful calculation
• Precision in dosage is vital for patient safety

Basics of Pharmacology Calculations

Pharmacology calculations are fundamental in medication administration, ensuring that patients receive the exact amount of medication needed without under or overdosing. These calculations involve various components, such as concentration, volume, and rate of administration.
In the heparin infusion scenario, we first determine the concentration, calculated as the amount of medication (units) per milliliter. With a concentration of 20 units/mL established in this case, it becomes straightforward to compute the hourly dosage when the infusion rate is known.
Learning how to quickly and accurately perform these calculations is essential for healthcare professionals. It ensures drugs are administered safely and effectively. Specific calculations, like dividing total heparin units by the volume of the solution to get concentration, are done routinely in clinical settings for various medications.

• Ensures correct medication dosing
• Involves concentration and volume understanding
• Essential skill for safe drug administration

Essentials of Medication Dosage Determination

Medication dosage determination involves not only understanding the medication details assigned to a patient but also accurately calculating how these details translate into a measurable dosage. In the context of heparin, healthcare providers must interpret medical orders to determine the appropriate infusion and dosage rates.
Here, the hourly dosage is computed by multiplying the concentration (20 units/mL) by the infusion rate (80 mL/hr). This calculation is fundamental in medication management, allowing a steady therapeutic level of heparin in the patient's bloodstream, effectively preventing or resolving clotting issues.
By grasping these calculations, nurses can confidently adjust doses as needed under a physician’s guidance, ensuring precise treatment outcomes. Moreover, these calculations prevent adverse effects associated with improper dosing, reinforcing the importance of mathematical precision in pharmacology.

• Translates medical orders into measurable dosages
• Involves calculating infusion and dosage rates
• Prevents adverse effects from incorrect dosing