Question

Order: Clonidine \(0.5 \mathrm{mg}\) p.o. t.i.d. Hold for blood pressure less than \(100 / 60\). Available: Clonidine tablets labeled \(0.1 \mathrm{mg}, 0.2 \mathrm{mg}, 0.3 \mathrm{mg}\) Which would be the best combination to administer to the client? ______

Short answer

The best combination is one 0.2 mg tablet and one 0.3 mg tablet.

Step-by-step solution

Understand the Prescription

The prescription order is for Clonidine to be taken by mouth (p.o.), three times a day (t.i.d.), with a dose of 0.5 mg each time. It should not be given if the patient's blood pressure is less than 100/60 mmHg.

Review Available Dosages

The available tablets are labeled 0.1 mg, 0.2 mg, and 0.3 mg. You need to find a combination of these to achieve the prescribed 0.5 mg dose.

Calculate Possible Combinations

To reach 0.5 mg, consider adding different tablet dosages together. Some options include: - Using five 0.1 mg tablets: 5 x 0.1 mg = 0.5 mg - Using one 0.2 mg tablet and one 0.3 mg tablet: 0.2 mg + 0.3 mg = 0.5 mg - Using two 0.2 mg tablets and one 0.1 mg tablet: 2 x 0.2 mg + 0.1 mg = 0.5 mg

Determine the Best Combination

The most convenient combination is one 0.2 mg tablet and one 0.3 mg tablet, as it minimizes the number of pills taken, making it easier for the patient to manage and reducing the likelihood of error.

Key concepts

Pharmacology

Pharmacology is the science of drugs, including their effects, mechanisms, and therapeutic uses. Understanding pharmacology is essential for calculating medication dosages accurately, ensuring effective treatment. When dealing with a medication like Clonidine, it is crucial to comprehend not only its purpose but also its pharmacological properties. Clonidine is a medication primarily used to treat high blood pressure. It works by stimulating certain receptors in the brain, which in turn relaxes blood vessels, leading to lowered blood pressure.

From a pharmacological perspective, knowing the different available dosages is vital. In this case, Clonidine comes in 0.1 mg, 0.2 mg, and 0.3 mg tablets. Each tablet strength needs to be understood so you can tailor the dosage to suit the prescription and the specific needs of the patient. This knowledge ensures that while the medication remains within therapeutic levels, it does not become toxic.

Patient Safety

Patient safety is a top priority in healthcare, especially when it comes to administering medications. Accurate dosage calculations are critical as they prevent overdosing or underdosing, both of which could harm the patient. In the exercise scenario, the prescription includes a special instruction: "hold for blood pressure less than 100/60."

This instruction is an essential part of patient safety. It requires the healthcare provider to monitor the patient's blood pressure before administering the drug. If the blood pressure is below the specified limit, Clonidine should not be given, as it could lower the blood pressure too much, potentially leading to dizziness, fainting, or more severe health consequences. This specific alert helps prevent adverse drug reactions and ensures the medication is given only when safe.

Prescription Interpretation

Interpreting a prescription correctly is an essential skill for healthcare providers. It involves reading and understanding every part of the doctor's order to administer medication safely and effectively. The exercise highlights the need to identify the right dosage form—oral tablets in this case—and how often it should be given (t.i.d., which means three times a day).

Moreover, prescription interpretation includes comprehending any additional instructions, like holding the medication for certain blood pressure conditions. This ensures the patient receives the medication in the correct dosage, at the right time, and under appropriate circumstances.

In this scenario, the task involves combining tablets to reach the prescribed dose of 0.5 mg. Successfully interpreting the prescription involves calculating and selecting the optimal combination of available tablets: using one 0.2 mg and one 0.3 mg tablet. This interpretation ensures clarity, reduces the number of pills, minimizes errors, and simplifies administration for patients.