Problem 1
Which drug produces transient muscle fasciculations followed by muscle paralysis that is not reversed by neostigmine? (A) rocuronium (B) hyoscyamine (C) cisatracurium (D) succinylcholine (E) pancuronium
Problem 2
Toxic doses of scopolamine would be expected to cause all of the following effects EXCEPT (A) hallucinations. (B) bronchospasm. (C) hyperthermia. (D) urinary retention. (E) blurred vision.
Problem 3
Topical ocular administration of tropicamide will cause (A) contraction of the ciliary muscle. (B) vasoconstriction. (C) miosis. (D) relaxation of the iris sphincter muscle. (E) lacrimation.
Problem 4
The therapeutic use of darifenacin is based on its ability to (A) relax bronchial smooth muscle. (B) relax urinary bladder smooth muscle. (C) relax uterine smooth muscle. (D) inhibit salivary secretions. (E) relax gastrointestinal muscle.
Problem 5
Sugammadex, used to reverse an overdose with neuromuscular blockers, has a unique mechanism of action best described as which one of the following? (A) agonist at cholinergic acetylcholine receptors. (B) antagonist at cholinergic acetylcholine receptors. (C) antagonist at muscarinic acetylcholine receptors. (D) forms an inactive drug complex. (E) inhibits acetylcholinesterase.
