Problem 1
What is the mechanism of the anthelmintic effect of pyrantel? (A) impaired microtubule function (B) decreased glucose uptake (C) free-radical production (D) inhibition of electron transport (E) neuromuscular blockade
Problem 2
A Peace Corps volunteer experiences severe anxiety and hallucinations while receiving malaria treatment. Which drug is most likely causing this adverse effect? (A) primaquine (B) artesunate (C) mefloquine (D) atovaquone (E) proguanil
Problem 3
A susceptible population is treated with ivermectin to prevent onchocerciasis (river blindness). The permeability of which ion is increased in the parasite by this treatment? (A) calcium (B) magnesium (C) potassium (D) sodium (E) chloride
Problem 4
Nitazoxanide is used to treat which infection in immunocompetent persons? (A) leishmaniasis (B) malaria (C) cryptosporidiosis (D) trypanosomiasis (E) toxoplasmosis
Problem 5
Which drug inhibits erythrocytic schizogony in malarial species by forming free radicals that damage heme and proteins? (A) pyrimethamine (B) artemether (C) atovaquone (D) proguanil (E) lumefantrine
