Problem 1
Which of the following terms best describes a receptor located on a neuronal terminal that binds a neurotransmitter released from another neuron and decreases release of neurotransmitter from the neuronal terminal? (A) presynaptic receptor (B) heteroreceptor (C) postsynaptic receptor (D) autoreceptor (E) ionotropic receptor
Problem 2
Neurotransmitters are made in neurons and released when vesicles fuse with the neuronal membrane. What name is given to this process? (A) apoptosis (B) phagocytosis (C) endocytosis (D) pinocytosis (E) exocytosis
Problem 3
Which one of the following statements best describes the differences between classical neurotransmitters and neuropeptides? (A) neuropeptides are synthesized in the cell body (B) classical neurotransmitters have a longer duration of action (C) neuropeptides undergo rapid reuptake into the presynaptic terminal (D) classical neurotransmitters are packaged into vesicles (E) neuropeptides are degraded by acetylcholinesterase in the synapse
Problem 4
A patient with metastatic lung cancer is treated for chronic pain with daily doses of a long-acting morphine formulation and oxycodone for breakthrough pain. He complains that the medicines are no longer working. Which one of the following mechanisms may explain the lack of effect of his medicines? (A) the metabolism of morphine is upregulated (B) pain intensity has greatly increased (C) the efficiency of \(G\) protein coupling is decreased (D) opioid receptors are downregulated (E) the patient is a "drug seeker" and addicted to opioid medications
Problem 5
Which one of the following drugs acts by inhibiting neurotransmitter reuptake? (A) lithium (B) morphine (C) fluoxetine (D) levodopa (E) donepezil
