Question

The cells responsible for bone resorption are ________.

1. osteoclasts
2. osteoblasts
3. fibroblasts
4. osteocytes

Short answer

The correct answer is option (a).

The cells responsible for bone resorption are osteoclasts.

Step-by-step solution

 Osteoclasts 

• The cells known as osteoclasts are responsible for breaking down bone to start the process of normal bone remodeling and for mediating bone loss in pathologic situations by escalating their bone resorption function.
• In osteoclasts, the process of resorbing, or destroying, bone matrix is carried out. .

Step: 1 Explanation for Correct answer

• Osteoclasts take responsibility for the long-term regulation of calcium in the blood homeostasis for bone resorption, which aids in bone remodeling.
• Osteoclastic connective tissue, cartilage, or bone is decomposed by a monocyte-derived cell called an osteoclast.
• The combining of precursor cells produces osteoclasts. Thus, the option a is correct.

Step: 2 Explanation for wrong answer

• Osteoblasts are in charge of creating new bone. So, option b is wrong.
• The fibroblast must maintain the integrity of the extracellular matrix (ECM). So, option c is wrong as well.
• Osteoclast viability might have a big impact on bone preservation and integrity. Hence, option d is wrong too.