Question

What is the consequence of mutation of a mismatch repair enzyme? How will this affect the function of a gene?

Short answer

Function of a gene may be affected or not be expressed.

Step-by-step solution

Step 1. Introduction

A mutation is a rare and random inheritable variation or alternation in the structure of genetic material in the genotype of an organism that is caused by some mutants.

Step 2. Explanation

The mismatch repair enzyme corrects the errors after replication is completed by removing the wrong nucleotide and adding the correct one. If there is any damage in the mismatch repair enzyme then it can create more permanent damage.

In the case of xeroderma pigmentosa, mutations are not repaired. In this gene function may be affected or it may not be expressed.