Question

Figure 10.14 Human papillomavirus can cause cervical cancer. The virus encodes E6, a protein that binds p53. Based on this fact and what you know about p53, what effect do you think E6 binding has on p53 activity? a. E6 activates p53 b. E6 inactivates p53 c. E6 mutates p53 d. E6 binding marks p53 for degradation

Short answer

The correct option is d.

Step-by-step solution

Step 1. Introduction

Human papillomavirus causes HPV infection which is transmitted through skin-to-skin contact. It is usually spread by sexual contact.

Step 2. Explanation of the correct option

Option d is correct because the normal function of p35 is to monitor DNA and supply oxygen when E6 protein when binds to p35 and p35 degraded and leading to abnormal cell division and causes cancer.

Step 3. Explanation of the incorrect option

Option a is correct because p35 degraded when the E6 protein binds.

Option b is correct because p35 degraded when the E6 protein binds.

Option c is correct because p35 degraded when the E6 protein binds.