Question

What would happen if the intracellular domain of a cellsurface receptor was switched with the domain from another receptor?

Short answer

Normal activation of the pathway occurs if switched with the receptor of another domain or extracellular domain.

Step-by-step solution

Step 1. Introduction

The cell-surface receptor is embedded in the plasma membrane and sends a signal from outside the cell to the cytoplasm. Their ligands do not enter the cell.

Step 2. Explanation

When the intercellular domain of the cell-surface receptor is replaced with the receptor of another or extracellular domain then also it would activate the pathway normally triggered by the receptor contributing intracellular domain.