Question

Which hormone stops acid secretion in the stomach?

a. gastrin

b. somatostatin

c. gastric inhibitory peptide

d. CCK

Short answer

Option B is the correct answer.

Step-by-step solution

Introduction

Hormones regulate the many digestive enzymes that are secreted in the stomach and intestine during the digestion and absorption process. As an illustration, the hormone gastrin causes the release of stomach acid to increase in response to eating.

The explanation for the correct answer

The correct option is B.

Somatostatin is produced in the gastrointestinal tract by enteric neurons, and pancreatic, intestinal, and gastric D cells. The majority of somatostatin's pharmacologic effects are inhibitory in nature. Somatostatin plays a key role in regulating the stomach's production of gastric acid. The gastrointestinal (GI) tract's gastric secretion, which is brought on by eating, is inhibited by somatostatin. Additionally, it limits the release of gastrin and secretin, two digestive hormones.

The explanation for incorrect options

• Option A (gastrin) - Water and bicarbonate ion secretion is stimulated by gastrin's action on the exocrine pancreas. So, it has nothing to do with the stoppage of acid secretion.
• Option C (Gastric Inhibitory Peptide)- Gastric secretion and motility are inhibited by GIP.
• Option D (CCK) - CCK promotes the release of bile juice and pancreatic enzymes via acting on the gall bladder and pancreas, respectively.

So, they are irrelevant options.